Heart Lesions and Hemorrhagic
نویسندگان
چکیده
Four trials with pigs and one trial with rats were conducted to determine the relationship of dietary sugar level, supplemental vitamin K, sodium salicylate, therapeutic levels of chlortetracycline and initial pig weight to development of sugar-induced heart lesions and hemorrhagic syndrome. The effects of crude vs. refined sucrose and glucose vs. sucrose were also compared. Each of the high sugar diets produced heart lesions and hemorrhagic syndrome in the pig. Vitamin K prevented both heart lesions and hemorrhagic syndrome in each of three trials with pigs. Rats aid not develop heart lesions nor was hemorrhagic syndrome apparent from eating these same high sugar diets. Antibiotic prevented heart lesions but did not prevent the hemorrhagic syndrome nor .lower prothrombin time in the pigs that were fed high sucrose diets. Diets containing either 63% glucose or 45% sucrose produced both conditions but to a lesser extent than did diets with 63% of either crude or refined sucrose. Lesions were more numerous and severity of lesions and hemorrhagic syndrome were greater when light pigs were started on high sugar diets. Both conditions occurred, however, among pigs that were started on test as heavy as 48 kilograms. Sodium salicylate did not prevent heart lesions or hemorrhagic syndrome.
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